Some of the original studies regarding SIRT1 have to do with how a "calorie restrictive diet" enabled the activation of SiRT1. Calorie restriction is a controversial diet that often comes under scrutiny by dietitians and medical professionals alike. On the other hand there are also many professionals who support the diet.
As I did the first time I heard of calorie restriction it sounded to me like a starvation diet. How could that be healthy I asked my self? To answer that question I had to do some research because without it I would just be jumping to an uneducated conclusion. What I learned was eye opening and I was able to see why both sides would argue it was healthy or not. I'll share with you my opinion at the end of the post.
Calorie Restriction is a lifestyle diet where you in-take less calories then your body is currently accustomed to. Usually the amount of calories per day is approximately 20% less then your Basal Metabolic Rate (BMR). For more information on calculating BMR check out this post on the "My Resveratrol Experience" web site. There is more to it then just cutting out some calories. The idea is to eat the appropriate foods and consume the appropriate vitamins and nutrients your body needs.
The theory behind calorie restriction activating SiRT1 is one that is controversial and not 100% proven yet in humans. It is said that when cells are lightly stressed it causes a defense mechanism to take place. This mechanism causes SiRT1 and other longevity genes to activate and push a cell to live. The light stress on cells is actually beneficial if these theories are proven true.
For me the question is when SiRT1 is activated can we "live longer" or just "live healthier" further into life. I guess time and future research will tell.
As for my views on a CR diet: I believe CR is an effective diet for those who have a strong mental stability and no previous "weight control" conditions such as anorexia and bulimia. If you decide to start a CR diet make a point to get baseline blood tests done so you have something to compare your diet results to.
It is also important to note when starting any diet you should check with your doctor to make sure it is right for you. Be conscious of any medications you take as the change in diet could effect how they react in your body.
Live Longer,
Markus
Comments